How much uric acid does a man need to have to suffer from gout

Uric acid will cause gout when it reaches a certain level. Once the uric acid content in urine exceeds the standard, it will cause gout. This is an indicator recognized by the medical community. Once the uric acid content in urine exceeds the standard, it will not only cause symptoms such as gout, but also cause other terrible diseases. So we must pay attention to it. If your uric acid content in urine exceeds the standard, you must pay attention to it during the examination process. Please ask some doctors about what complications this problem will cause.

Normal blood uric acid levels: 237.9-356.9 micromoles (4-6 mg/L) for adult males, 178.4-297.4 micromoles (3-5 mg/L) for females. The normal reference value for females is about 60-70 micromoles lower than that for males. Usually, the uric acid level gradually increases after menopause and approaches that of adult males. Generally, a blood uric acid level of more than 420 micromoles is defined as hyperuricemia. However, the normal reference value for each hospital or laboratory will vary and should be determined based on the specific situation. Only 5-12% of patients with hyperuricemia will develop gout, and the rest will not have any symptoms. Therefore, high uric acid levels do not mean gout. Most cases of hyperuricemia can persist without symptoms throughout life, but the higher the blood uric acid level and the longer it persists, the greater the chance of developing gout and urinary stones. Therefore, hyperuricemia is an important biochemical basis for gout.

The most important biochemical basis of gout is hyperuricemia. A normal adult produces about 750 mg of uric acid per day, of which 80% is endogenous and 20% is exogenous. This uric acid enters the uric acid metabolic pool (about 1200 mg). About 60% of the uric acid in the daily metabolic pool is metabolized, of which 1/3, about 200 mg, is broken down and metabolized through the intestines, and 2/3, about 400 mg, is excreted through the kidneys, thereby maintaining the stability of the uric acid level in the body. Problems in any of these links can lead to Hyperuricemia gout is a lens-related arthropathy caused by monosodium urate (MSU) deposition. It is directly related to hyperuricemia caused by purine metabolism disorder and (or) decreased uric acid excretion. It specifically refers to acute characteristic arthritis and chronic tophi disease, mainly including acute paroxysmal arthritis, tophi formation, tophi chronic arthritis, uric acid nephropathy and uric acid urinary tract stones. In severe cases, joint disability and renal insufficiency may occur. Gout is often accompanied by abdominal obesity, hyperlipidemia, hypertension, type 2 diabetes and cardiovascular disease.

In fact, many diseases in life can be predicted in advance through some small changes in the body. For example, if you are always sleepy and your heart beats fast recently, you need to go to the provincial hospital to check if there are any problems with your cardiovascular and cerebrovascular system. Just like an earthquake, it is impossible for any disease to occur without any signs. The specific value of uric acid that causes gout is still under scientific research.