What disease does a blister on the glans cause?

The glans of a man refers to the front end of the penis. It is called the glans because it looks like the head of a turtle. In life, the most common glans problem men encounter is foreskin. However, this situation is easy to deal with. You just need to go to the hospital for a simple circumcision surgery. So, what is the disease of a blister on the glans?

Hirsuties papillaris genitalis, also known as penile pearly papules, coronal sulcus or glans papules, is also called hairy penis or multi-papillary penis by some scholars. Currently, most scholars believe that this is a normal physiological variation, so it will not affect health and will not be infected or spread through sexual intercourse.

Causes

The cause and incidence of penile pearly papules are still unclear. Some scholars believe that this disease is a kind of abnormal physiological development. Some scholars believe that it is related to prepuce. Surveys have found that the incidence of penile pearly papules in young men with prepuce is significantly higher than that in men with normal prepuce. Some scholars believe that this disease may be related to HPV infection, but Ferenczy et al. and Zhang Kaijin et al. tested HPV in the lesion tissue and found no HPV. The author observed that the direct cause of this disease may be inflammatory reactions such as local redness and swelling caused by prepuce, poor local hygiene, long-term stimulation of coronal sulcus secretions and dirt, or other factors such as infection. If the patient needs treatment, it can be treated through laser surgery, cryotherapy, and drug therapy.

Clinical manifestations and diagnosis

Pearly penile papules are more common in men around 20-30 years old. The damage mainly occurs at the junction of the edge of the glans penis and the coronal sulcus and/or the frenulum. The lesions are 1-3mm in size, and the lesions are larger on both sides of the frenulum. The top of the papules is round and smooth, and some papules are hairy or thread-like. The papules are mostly not fused with each other, and are densely arranged in one or more rows. They are obvious on the dorsal side of the glans penis and may partially or completely surround the glans penis. The color of the lesions is mostly pearly white, a few are light red or skin-colored, and some may appear mildly red and swollen. There is no tenderness, no rupture, and the patient has no subjective symptoms.

The key point in differentiating and diagnosing penile pearly papules and condylar warts is that in the former, the lesions are limited to the edge of the glans, the number of lesions is larger, they are pearly milky white papules with a smooth surface, the lesions do not increase in size as the course of the disease prolongs, and the acetic acid test is negative; while in the latter, the lesions are not limited to the edge of the glans, they are mostly single and scattered, the lesions are larger, the surface is not smooth, and they are mostly cauliflower-shaped, they gradually increase in size as the course of the disease prolongs, the acetic acid test is positive, and concave cells are found in histopathological examination.