Is it likely that my father has cleft lip?

People often call it cleft lip, which is clinically called cleft lip. It is a congenital deformity. In medicine, the cleft lip of babies is divided into first, second and third degrees according to the severity. If it is a third degree cleft lip, the situation is the most serious and may be a complete cleft lip. At this time, surgical treatment must be performed as soon as possible. So if a man has a cleft lip, what is the probability of passing it on to the next generation?

Is it likely that my father has cleft lip?

Cleft lip can be inherited. The incidence of cleft lip in the population is 0.17%. If one parent has cleft lip, the incidence of their children can be as high as 2.6-5.6%, which is 12-32 times higher than the former.

Guidance:

The chance of this happening should be smaller, but we still need to do preventive work. Eating more folic acid can reduce the chance of cleft lip in babies. In addition, both parties should pay attention to supplementing nutrition during pregnancy and before pregnancy to achieve a balanced nutrition. In addition, when the fetus is 20 to 24 weeks old, an experienced doctor can see from the ultrasound examination whether the fetus has more obvious deformities such as limb defects. However, cleft lip can now be completely cured, so there is no need to worry.

Generally, cleft lip is a rare abnormality and is not a hereditary disease. It is usually caused by infection during pregnancy or other factors. Don't worry, the chance of inheritance is very small.

Guidance:

You can take folic acid tablets one month before pregnancy to prevent it.

It is not very big. It is recommended to do regular pregnancy tests during pregnancy.

Guidance:

Generally, in the middle or late stages of pregnancy, you can have an amniocentesis or B-ultrasound to check whether the baby has a cleft lip.

Is cleft lip hereditary and how to avoid it? Cleft lip is medically called cleft lip, and it has a certain hereditary probability of about 4~5%. There is no regulation that patients with cleft lip cannot get married. If you get pregnant after marriage, it is recommended not to smoke or drink, not to take medicine casually, and to have a good growth environment during pregnancy, which can reduce the probability of cleft lip.

The main causes of cleft lip include the following:

1. Genetic factors: Patients with cleft lip may find similar deformities in their direct or collateral relatives, so it is believed that cleft lip deformity is related to genetics. Epidemiological surveys show that the incidence of cleft lip in the offspring of direct relatives with cleft lip deformity is higher than that of relatives without cleft lip deformity. Genetic studies also believe that cleft lip is a polygenic genetic disease.

2. Smoking and drinking factors: Data show that pregnant women who smoke heavily (including passive smoking) and drink alcohol in the early stage of pregnancy have a higher incidence of cleft lip and palate in their children than pregnant women who do not smoke or drink.

3. Drug factors: Vitamin deficiency during pregnancy, the use of hormones or anti-tumor drugs, etc. may lead to fetal malformations.

4. Environmental factors: Virus infection during pregnancy, exposure to X-rays, microwaves, mechanical damage, environmental pollution, hypoxia, etc. can all cause genetic mutations.