To confirm the diagnosis of thyroid follicular nodules, these tests are required clinically

1. Serological examination

Abnormal thyroid function does not exclude thyroid cancer but indicates that it is less likely. Hyperthyroidism or decreased TSH are both indicative of autonomous functional thyroid adenoma, nodules, or toxic multinodular thyroid. Patients with medullary thyroid carcinoma have elevated serum calcitonin levels, but pentagastrin and calcium stimulation are required in the early stages of C-cell proliferation.

2.Nuclide scanning

Scanning is of little value in differentiating benign from malignant lesions. Most benign and malignant solid nodules are hypofunctional relative to the surrounding normal glandular tissue, so the detection of cold nodules is rarely specific, and the overlapping radionuclide absorption of the surrounding normal glandular tissue may miss small nodules. Many thyroid cancers can absorb Tc, so there is still a proportion of cancer cases among hot nodules.

3. Ultrasound diagnosis

Ultrasound is very reliable in diagnosing cystic lesions. It has little value in distinguishing benign from malignant lesions. However, it is very meaningful in determining the size and location of nodules and guiding the positioning of puncture.