What to do if men have anti-sperm antibodies in their blood

Under normal circumstances, the testicles and male reproductive tract have a strong immune barrier, and sperm cannot come into contact with the body's own immune system, so immune reactions rarely occur. The appearance of anti-sperm antibodies in the blood is generally caused by disease. What should men do if they have anti-sperm antibodies?

Antisperm antibody expression

In infertility, both men and women may have anti-sperm and anti-body positivity. For men, the main manifestations are decreased sperm quality, decreased vitality, substandard motility, and even a large number of abnormal sperm, which makes some seemingly healthy men lose their normal reproductive ability unknowingly, although they feel very surprised and helpless.

Antisperm Antibody Therapy

Immunosuppressive therapy

In clinical practice, adrenal cortex hormones are often used, with several methods including local application, low-dose continuous administration, high-dose intermittent administration and shock administration. The purpose of immunosuppressive therapy is to suppress the body's immune response and reduce the titer of anti-sperm antibodies. Of course, immunotherapy has great side effects, and experts do not recommend patients to use it.

Isolation therapy

This treatment is to use condoms to avoid and reduce the contact between the female reproductive tract and sperm and its antigenic substances, without producing new antibodies. Generally, the patient is isolated for 6-12 months, and the anti-sperm antibody titer in the serum and cervical mucus is followed up. After it returns to normal, conception is possible.

If you have been married for many years without having children and your semen test is normal, you must have a blood test to confirm whether there are anti-sperm antibodies in your semen and blood.