Metronidazole sustained-release tablets instructions: Are there any adverse reactions?

Metronidazole sustained-release tablets is a drug name, generally used to treat vaginal inflammation in women. The main ingredient of the drug is the well-known metronidazole. In the actual application process, few patients will read the instructions carefully, resulting in adverse reactions. Let's follow the editor to take a look at the contents of the metronidazole sustained-release tablets instructions.

Ingredients

The active ingredient of this product is metronidazole, and its chemical name is 2-methyl-5-nitroimidazole-1-ethanol.

Characteristics

This product is a light yellow oval film-coated tablet, which appears off-white after removing the coating.

Adaptation

Treat bacterial vaginosis in women.

Specifications

750mg/tablet.

Dosage

Oral administration: 750 mg (1 tablet) once a day for seven consecutive days. Seven days is one course of treatment. Metronidazole sustained-release tablets should be swallowed whole on an empty stomach at least 1 hour before or 2 hours after a meal. Taking on an empty stomach can maintain the best sustained-release properties of this product.

Adverse reactions

In two multicenter clinical studies, 270 patients took metronidazole extended-release tablets orally, 750 mg once a day, for 7 consecutive days, and 287 patients took a control drug vaginally, once a day, for 7 consecutive days.

Most adverse events were mild to moderate, with 10% of patients complaining of headache and less than 2% of patients complaining of nausea being severe. Nine percent complained of a metallic taste in the mouth.

Vulvar and vaginal candidiasis is caused by various antimicrobial treatments. In this multicenter clinical trial, there was no statistically significant difference in the incidence of yeast vaginitis between the experimental group and the control group.