Why do boys have enlarged breasts?

There are many common diseases in men. To treat male diseases, we need to first understand male diseases, so that we can have a good method when relieving them. Drugs are the best choice for treating male diseases. Drugs are very effective in relieving male problems, and this treatment method has no effect on the body. This can also be done for male breast hypertrophy. But what is the cause of male breast hypertrophy?

Male breast enlargement:

Causes

1. Primary gynecomastia

It is more common in children and adolescents, often due to physiological endocrine disorders, with plasma estradiol levels higher than testosterone levels, resulting in a transient estrogen/androgen imbalance, or increased sensitivity of breast tissue to estrogen, also known as physiological male breast hypertrophy.

(ii) Secondary gynecomastia

1. Endocrine diseases

(1) Testicular diseases are caused by hypogonadism, very low androgen secretion, and changes in the ratio of testosterone to estrogen in the blood, which lead to male breast hypertrophy. ① Congenital testicular dysgenesis (Klinefelter syndrome); ② Complete testicular feminization; ③ Kallmann syndrome; ④ Orchitis, trauma and tumor; ⑤ Reifenstein syndrome.

(2) Adrenal diseases such as adrenal cortical hyperplasia, benign tumors, malignant tumors and decreased function. Such tumors can directly secrete estrogen or produce excessive estrogen precursors (such as androstanone), which are converted into effective estrogen in the tissues, increasing blood estradiol and causing breast hypertrophy.

(3) Thyroid diseases such as hyperthyroidism, increased concentration of sex hormone-binding globulin in plasma, excessive bound androgens, increased free estradiol (unbound estradiol), increased estrogen/testosterone ratio, and hormonal imbalance, which stimulates breast tissue proliferation and leads to male breast enlargement.

2. Other non-endocrine diseases

(1) Liver diseases such as hepatitis, cirrhosis, liver cancer, etc., accompanied by decreased liver function, often cause breast hypertrophy.

(2) Recovery period of chronic malnutrition: During malnutrition, the secretion of gonadotropin decreases. When malnutrition is corrected, a phenomenon reminiscent of second puberty occurs, and breast hypertrophy occurs, which is called "feeding-induced breast hypertrophy."

(3) Bronchogenic carcinoma and chronic lung diseases such as oat cell carcinoma, tuberculosis, and pectoris abscessus can cause breast hypertrophy due to local irritation.

(4) Chronic renal failure: Patients with uremia caused by chronic renal failure have been tested to have relatively elevated estrogen and prolactin levels in their blood, leading to breast development and hypertrophy.

(5) Diseases of the nervous system such as paralysis caused by high spinal cord lesions, syringomyelia, and hereditary movement disorders may be accompanied by breast hypertrophy.

(6) Long-term use of estrogen for treatment of prostate hyperplasia or prostate cancer may often cause male breast enlargement.

(7) Lymphatic system diseases such as lymphoma, malignant histiocytoma, myeloma and other reticuloendothelial system diseases are also rare causes of male breast development.

(8) Drug-induced breast enlargement: Gonadotropins such as chlorpromazine, cimetidine, methyldopa, metoclopramide, metronidazole, isoniazid, reserpine, meconium, and thyroid extract can bind to estrogen receptors and cause endocrine disorders in the body, which can lead to male breast development. However, the enlarged breasts can usually recover after stopping the drug.

(9) Other diseases such as cardiovascular disease (hypertension, heart disease), severe skin diseases (leprosy, exfoliative dermatitis), autoimmune diseases (rheumatic arthritis, rheumatoid arthritis), leptospirosis, ulcerative colitis, etc. may sometimes be accompanied by male breast development.

After understanding the causes of male breast hypertrophy, when improving male breast hypertrophy, it is important to note that men must actively cooperate during the treatment process. Many men do not cooperate with the treatment when treating such a disease, which does not help improve their own disease. Men should also pay attention to this.