Nowadays, many teenagers suffer from congenital testicular dysplasia, and the number is quite large. Testicles are the organs that secrete male hormones in men, so testicles play an important role in the male body. So why do some people have congenital testicular dysplasia? Today, let's introduce to you the causes of testicular dysplasia. Congenital dysgenesis of spermatic tubules, also known as Klinefelter syndrome, is a common genetic disease of sex chromosome aberration. The characteristics of this disease are that the patient has a testicular-like body shape, male breast development, small testicles, azoospermia, and increased gonadotropin in urine. The sex chromosomes of patients with this disease are 47,XXY, which means that there is one more X chromosome than normal men, so this disease is also called 47,XXY syndrome. The cause of congenital dysgenesis of spermatic tubules is that the sex chromosomes do not separate during the process of meiosis of the parents' reproductive cells to form sperm and eggs. During the maturation and division of the egg cell, the sex chromosomes do not separate, forming an egg containing two Xs. If this egg combines with a Y sperm, it will form a 47,XXY fertilized egg. If the XY does not separate during the first maturation and division of the spermatogenic cell during the maturation process, an XY sperm will be formed. This sperm can also combine with the X egg to form a 47,XXY fertilized egg. Patients with congenital dysgenesis of the sperm ducts have no abnormalities in childhood, and often develop abnormalities in adolescence or adulthood. Patients are tall, with long and thin lower limbs, delicate skin, shrill voice, no beard, and little body hair. About half of the patients have enlarged breasts on both sides. The external genitalia often resembles that of a normal male, but the penis is shorter than that of a normal male, the testicles on both sides are significantly reduced, mostly less than 3 cm, hard in texture, poor sexual function, no sperm in the semen, and patients often seek treatment for infertility or sexual dysfunction. Intellectual development is normal or slightly lower. Long-term supplementation of male hormones to improve secondary sexual characteristics, but the effect is not ideal. Generally, testosterone propionate (testosterone propionate) or methyltestosterone (methyltestosterone) tablets are taken sublingually. It is more convenient to give long-acting testosterone such as testosterone enanthate or testosterone cypionate. It is also possible to consider giving chorionic gonadotropin at the same time. Drugs only help masculinization to a certain extent, but cannot change female breasts, so for those with breast hypertrophy, the breasts and fat tissues can be removed. The above are some of the characteristics of congenital testicular dysgenesis introduced by professionals. Therefore, we should pay attention to this disease, but we should not be afraid, because it can be cured. In addition, patients should maintain a good attitude every day and not feel inferior in front of others, which will help the condition to improve. |
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