Prostate hyperplasia

In fact, prostate hyperplasia is a milder prostate disease compared to other prostate diseases, but after suffering from prostate hyperplasia, patients will feel obvious urination difficulties. In particular, the probability of middle-aged men suffering from prostate hyperplasia is very high, so middle-aged men should take some measures to prevent prostate hyperplasia in their daily lives. At this time, it is also very necessary to understand the causes of prostate hyperplasia.

Causes of prostate hyperplasia

1. The role of sex hormones

The presence of functional testicles is a necessary condition for the occurrence of prostate hyperplasia, and its incidence increases with age. Testosterone is a sex hormone in the male body. In the prostate, testosterone is converted into dihydrotestosterone with stronger action ability through the action of 5α-reductase. Dihydrotestosterone can promote the increase of prostate cells and gradually increase the volume of the prostate. Inhibiting the action of 5α-reductase in the body will reduce the production of dihydrotestosterone, the number of prostate cells will decrease, and the volume of the prostate will shrink. Some people also believe that there is a synergistic effect of estrogen and androgen in the development and change of prostate hyperplasia, and the change in the balance of estrogen and androgen is the cause of prostate hyperplasia.

2. Prostate cells reawaken the embryo

Studies have found that the initial pathological changes of prostatic hyperplasia, namely the formation of hyperplastic nodules, only occur in an area accounting for 5%-10% of the prostate gland, namely the transitional zone close to the prostatic sphincter and the periurethral area located on the inner side of this sphincter. The initial change of prostatic hyperplasia nodules is the proliferation of glandular tissue, that is, the original glandular ducts form new branches, grow into the nearby stroma, and form new structural structures (i.e. nodules) after complex re-branching. McNeal proposed the embryonic reawakening theory of prostatic hyperplasia based on the basic characteristic of embryonic development, which is the formation of new structures. He believed that the formation of prostatic hyperplasia nodules is the result of a prostatic stromal cell spontaneously transforming into an embryonic development state during the growth process.

3. Polypeptide growth factors

Peptide growth factors are a class of polypeptide substances that regulate cell differentiation and growth. Studies have shown that peptide growth factors can directly regulate the growth of prostate cells, while sex hormones only play an indirect role. Currently, the peptide growth factors that play an important role in the occurrence of prostate hyperplasia mainly include: epidermal growth factor (EGF), transforming growth factor α and β, fibroblast growth factor (FGF) and insulin-like growth factor-Ⅰ, among which alkaline fibroblast growth factor (bFGF) has been confirmed to have the effect of promoting mitosis of almost all cells in human prostate homogenate, and its role in the pathogenesis of prostate hyperplasia is receiving increasing attention.

4. Lifestyle

Obesity is positively correlated with prostate volume, that is, the more fat, the larger the prostate volume. Although the conclusions are not consistent, some existing studies have shown that nutrients can affect the risk of BPH and LUTS. Increased intake of total energy and total protein, as well as increased intake of fat, milk and dairy products, red meat, grains, poultry, and starch can potentially increase the risk of prostate hyperplasia and prostate surgery; while vegetables, fruits, polyunsaturated fatty acids, linoleic acid, and vitamin D have the potential to reduce the risk of prostate hyperplasia.

What are the health care methods for prostate hyperplasia?

1. Use drugs with caution. Some drugs can aggravate dysuria and can cause acute urinary retention when taken in large doses. These drugs mainly include atropine, ephedrine tablets, isopropyl epinephrine, etc. These drugs should be used with caution. In recent years, it has been found that calcium blockers and isoprenaline can promote prolactin secretion and weaken the contraction of the detrusor muscle, aggravating dysuria. Therefore, certain drugs should be used with caution or at best not at all.

2. Timely treatment of diseases that cause prostatic hyperplasia. Prostatitis, cystitis, and urethral stones should be treated promptly and thoroughly. This is also one of the health care measures for prostatic hyperplasia.

3. Massage the lower abdomen. How to take good care of prostate hyperplasia? Massaging the lower abdomen and pressing the Qihai, Guanyuan and other acupoints under the umbilicus can help restore bladder function. Applying a little pressure massage after urination can promote bladder emptying and reduce residual fluid.

4. Prevent cold. From late autumn to early spring, the weather is changeable. Cold weather often aggravates the condition of prostate hyperplasia. Therefore, patients must pay attention to keeping warm and prevent colds and upper respiratory tract infections.

5. Absolutely avoid drinking alcohol, as it can cause congestion and edema of the prostate and bladder neck and induce urinary retention.

6. Eat less spicy food. Spicy and irritating food can not only cause congestion of sexual organs, but also aggravate the symptoms of hemorrhoids and constipation, compress the prostate, and aggravate urination difficulties.