Pearly rash inheritance

Pearly rash gets its name because after the onset of the disease, some rashes similar to small blisters will appear on the epidermis, like crystal clear pearls. It often grows in sensitive areas, such as the genital system, causing redness and swelling on the surface, and may even cause infection, which is very harmful.

Introduction

Hirsuties papillaris genitalis, also known as penile pearly papules, coronal sulcus or glans papules, is also called hairy penis or multi-papillary penis by some scholars. Currently, most scholars believe that this is a normal physiological variation, so it will not affect health and will not be infected or spread through sexual intercourse.

Causes

The cause and incidence of penile pearly papules are still unclear. Some scholars believe that this disease is a kind of abnormal physiological development. Some scholars believe that it is related to prepuce. Surveys have found that the incidence of penile pearly papules in young men with prepuce is significantly higher than that in men with normal prepuce. Some scholars believe that this disease may be related to HPV infection, but Ferenczy et al. and Zhang Kaijin et al. tested HPV in the lesion tissue and found no HPV. The author observed that the direct cause of this disease may be inflammatory reactions such as local redness and swelling caused by prepuce, poor local hygiene, long-term stimulation of coronal sulcus secretions and dirt, or other factors such as infection.

Clinical manifestations and diagnosis

Pearly penile papules are more common in men around 20-30 years old. The damage mainly occurs at the junction of the edge of the glans penis and the coronal sulcus and/or the frenulum. The lesions are 1-3mm in size, and the lesions are larger on both sides of the frenulum. The top of the papules is round and smooth, and some papules are hairy or thread-like. The papules are mostly not fused with each other, and are densely arranged in one or more rows. They are obvious on the dorsal side of the glans penis and may partially or completely surround the glans penis. The color of the lesions is mostly pearly white, a few are light red or skin-colored, and some may appear mildly red and swollen. There is no tenderness, no rupture, and the patient has no subjective symptoms.