Treatments for vasospasm, cardiovascular spasm treatment

The cardiovascular system is an extremely important system for the human body. If there is a problem with the cardiovascular system, it will not only hinder the blood supply to the human body, but also cause damage to our heart. If the cardiovascular system has spasms, how should it be treated? At present, there are two main methods for treating cardiovascular diseases: drug treatment and surgical treatment.

1: Early use of cerebral vasodilators and volume expanders can significantly reduce and terminate TIA clinical attacks. Betazine 20mg added to 500ml of 5% glucose, or low molecular weight dextran or 706 generation plasma 500ml intravenous drip can be used. Vinaroton, Sibelium, etc. may also have a certain effect.

2: Antiplatelet aggregation agents can reduce the occurrence of microemboli. For patients without ulcer disease or hemorrhagic diseases, aspirin is often used for treatment, ranging from 50mg to 300mg per day. Most people think that a smaller dose is appropriate, and the dose can be reduced if taken for a long time. Dipyridamole (25mg 3 times a day) can be used in combination with aspirin to have a synergistic effect and can reduce the dose of aspirin. If the patient is not suitable for aspirin or the aspirin effect is not ideal, ticlopidine (Ticlopidine 200-250mg 1-2 times a day) or ticlid 250mg, once a day) can be used instead. During treatment, attention should be paid to strengthening the prevention and treatment of toxic side effects such as bleeding.

3: Anticoagulant therapy: For patients with frequent attacks, severe and progressively worsening conditions and no obvious contraindications to anticoagulant therapy, early anticoagulant therapy is of positive significance in reducing attacks and preventing cerebral infarction. Heparin 12500U is commonly added to 5% glucose saline for slow intravenous drip. At the same time, 300mg of new dicoumarol or 100-200mg of dicoumarol or 4-6mg of warfarin can be taken orally on the first day. Check the prothrombin time and activity every day, and measure it once a week after stabilization to adjust the oral dosage. The intravenous coagulation time is required to be maintained at 20-30 minutes and the prothrombin activity at 15-25%. The maintenance dose is 150-225 mg of cypermethrin, 25-75 mg of cypermethrin or 2-4 mg of warfarin. During treatment, attention should be paid to preventing and treating bleeding complications. The dose should be gradually reduced after discontinuation of the drug to avoid a "rebound effect". Since this treatment is difficult to control the dosage and has many bleeding complications, it is rarely used in China.

4: Calcium antagonists can selectively act on the calcium channels of cerebral vascular smooth muscle, preventing calcium ions from flowing from outside the cells into the cells, and have the effects of preventing cerebral artery spasms, dilating blood vessels, increasing cerebral blood flow and maintaining the ability of red blood cells to deform. Generally, 5-10 mg of Sibelium is used, once a day.

5: Other methods such as extracorporeal anti-pulsation, ultraviolet light quantum therapy and blood dilution, as well as Chinese medicines such as Chuanxiong and Danshen that can promote blood circulation, remove blood stasis, and promote menstruation can also be used.

1: If angiography confirms that the large cervical arteries have obvious stenosis or occlusion, and the drug response is poor, and the patient's general condition allows and conditions permit, internal cervical artery endarterectomy, stent placement, or intracranial and extracranial vascular anastomosis can be considered. It has a certain effect on eliminating microembolism, improving cerebral blood flow, and establishing collateral circulation. Since it is not a radical cure and the surgical indications and effects have not yet been confirmed, it is still rarely used in China.

The problem will bring great trouble, so we must protect our cardiovascular health.