How to treat an enlarged prostate?

Prostate problems are a problem that many men have now. Many times, there will be some cases of prostate hyperplasia. Because many people do not understand, they do not know what to do when they encounter this situation, which will cause some problems. So, let me introduce to you how to treat an enlarged prostate?

The harmfulness of prostatic hyperplasia lies in the pathological and physiological changes caused by lower urinary tract obstruction. The pathological individual differences are very large, and not all of them are progressive. Some lesions will no longer develop after reaching a certain degree, so even if mild obstruction symptoms occur, surgery is not always required.

1. Observe and wait

If the symptoms are mild and the IPSS score is below 7, the condition can be observed and no treatment is required.

2. Drug treatment

(1) 5α-reductase inhibitors Studies have shown that 5α-reductase is an important enzyme for the conversion of testosterone to dihydrotestosterone. Dihydrotestosterone plays a certain role in prostate hyperplasia, so the use of 5α-reductase inhibitors can inhibit hyperplasia to a certain extent.

(2) α-receptor blockers: It is currently believed that this type of drug can improve urinary tract dynamic obstruction, reduce resistance and thus improve symptoms. Commonly used drugs include Gotelin, etc.

(3) The most widely used anti-androgen drugs are progesterone drugs. They can inhibit the cellular binding and nuclear uptake of androgens, or inhibit 5α-reductase and interfere with the formation of dihydrotestosterone. Progesterone drugs include megestrol acetate, cyproterone acetate, chlormadinone acetate, and progesterone caproate. Flubutamide is a non-steroidal anti-androgen drug that can also interfere with the cellular uptake and nuclear binding of androgens. After using anti-androgen drugs for a period of time, symptoms and urine flow rate can be improved, residual urine can be reduced, and the prostate can be reduced. However, after stopping the drug, the prostate will enlarge again and symptoms will recur. In recent years, it has been found that this type of drug can increase blood viscosity and increase the incidence of cardiovascular and cerebrovascular embolism. Luteinizing hormone-releasing hormone analogs have a highly selective effect on the pituitary gland, causing it to release LH and FSH. Long-term use can exhaust this function of the pituitary gland, reduce the ability of the testicles to produce testosterone, or even make it impossible to produce testosterone, thus achieving the effect of drug removal of the testes.

(4) Others include M receptor antagonists, herbal preparations, and traditional Chinese medicine. M receptor antagonists block bladder M receptors, relieve excessive detrusor contraction, and reduce bladder sensitivity, thereby improving the urinary symptoms of BPH patients. Herbal preparations such as Prosperide are suitable for the treatment of BPH and related lower urinary tract symptoms.

In summary, a comprehensive assessment of the condition should be made before drug treatment, and the side effects of the drugs and the possibility of long-term medication should also be fully considered. Long-term follow-up should be conducted to observe the effects of drug treatment, and urodynamic tests should be performed regularly to avoid delaying the timing of surgery.

How to treat an enlarged prostate? This question has been introduced in detail above, and we also know how to treat this disease. In this way, we can better avoid some problems. At the same time, we remind patients who encounter this situation not to worry but to insist on the correct way to treat it.