Causes of itching in male genitals

In fact, in daily life, many people do not have time to take care of their bodies, which will directly lead to abnormal changes in their bodies, such as itching in male genitals. Let us now understand the causes of itching in male genitals.

main reason:

1. Genetic disease: There are reports of mothers and daughters, and sisters in a family suffering from the disease at the same time, and it is found that the positive rate of HLA-B40 antigen in patients is significantly higher than that in women without the disease, so this disease is closely related to HLA-B40.

2. Autoimmune diseases: It has been reported that about 21% of patients have concurrent autoimmune diseases such as diabetes, hyperthyroidism or hypothyroidism, vitiligo, pernicious anemia, alopecia areata, etc., and there is lymphocyte infiltration in the epidermis, indicating an immune response in local tissues. It is speculated that this disease may be related to subepithelial damage caused by autoanti-collagen antibodies.

3. Sex hormone deficiency. Because the lesions of prepubertal patients can be alleviated after menarche, it is believed that it may be related to estrogen deficiency, but clinical estrogen treatment is ineffective. Some scholars reported that the dihydrotestosterone and androstenedione in the patient's serum decreased, while free testosterone increased. Local application of testosterone treatment was effective. After treatment, total testosterone and dihydrotestosterone in the blood increased. The author speculated that it may be related to the decrease in 5α-reductase activity, which led to the obstruction of testosterone to dihydrotestosterone conversion. However, in patients with 5α-reductase deficiency, the risk of lichen sclerosus did not increase. Recently, it has been reported that corticosteroid treatment is effective in patients with androgen receptor deficiency.

4. Infectious factors In recent years, some people have found that some patients with vulvar lichen sclerosus are accompanied by spirochetal infection, suggesting that spirochetes may be the cause of this disease.

5. Neurovascular dystrophication Neurovascular dystrophication in the deep connective tissue of the vulva causes the skin covering it to become diseased. Someone exchanged the diseased skin of the vulva with the normal skin of the patient's thigh and found that the diseased skin transplanted to the thigh gradually turned normal, while the normal skin transplanted to the vulva developed sclerotic lichen. Therefore, it is proposed that local neurovascular dystrophication is the cause of this disease.

Although clinical observations have shown that the above-mentioned various phenomena appear to be related to the onset of the disease, they have not yet been confirmed and generally recognized.

The above article introduces in detail the causes of male genital itching. I believe everyone has a preliminary understanding of it. Therefore, in daily life, if such a situation occurs, you should go to the hospital for a detailed examination in time.