The harm of pyridine to boys

Pyridine, an organic chemical compound, is a six-membered heterocyclic compound with a nitrogen molecule. It can be regarded as a compound in which a (CH) in the benzene molecule structure is replaced by N, so it is also called nitrogen benzene. It is a colorless or slightly yellow liquid with a foul odor. Pyridine and its homologues exist in bone nicotine, medium-temperature coal tar, liquefied gas, shale oil, and crude oil.

Production of pharmaceutical efficacy and effects The vaccine is a carboxamide compound of sodium salicylate and sulfapyridine. After oral administration, most of it is converted into 5-aminosalicylic acid (mesalazine) and sulfapyridine by microorganisms in the alkaline gastrointestinal environment. The latter is digested and has a weak antibacterial effect. It plays an important role as a mediator in the drug molecular formula, preventing 5-aminosalicylic acid from being digested in the stomach and duodenum. Under alkaline conditions in the gastrointestinal tract, intestinal microorganisms cleave the diazo bond and release 5-aminosalicylic acid, which fully exerts its anti-infection and immunosuppressive effects. It is used for the treatment of mild ulcerative colitis, auxiliary treatment of mild to moderate ulcerative colitis, and prevention of ulcerative colitis.

After oral administration, part of the drug is digested in the digestive system and can re-enter the gastrointestinal tract (enterohepatic circulation) through bile. The undigested drug is dissolved by pathogens in the tail of the ileum and sigmoid colon into 5-aminosalicylic acid (5ASA) and sulfapyridine. The vast majority of the remaining drug is excreted in the feces. After digestion, sulfapyridine is metabolized in the liver and metabolized by the kidneys, while only 1/3 of mesalamine is digested, and the rest is excreted with feces after having a therapeutic effect in the gastrointestinal tract.

Production operation method and demand vaccine demand for adolescents: oral, >2 years old, 10~15mg/kg each time, 4 times a day, after the symptoms are relieved, it can be changed to a maintenance dose of 7.5~10Mg/kg each time, 3 or 4 times a day. Adult demand: oral, 0.5~7.5g each time, 4 times a day, if there is no manifestation, it can be gradually increased to 1~1.5g each time, 4 times a day, the maximum demand is 8g per day, after the symptoms are relieved, it can be changed to a maintenance dose of 0.5g each time, 3 or 4 times a day.

Common production problems, side effects and damages: Vaccine blood pressure, skin allergy to this product or sulfonamides, sodium salicylate drugs, <2-year-old adolescents are strictly prohibited from using it. Patients with platelet deficiency, granulocytopenia, gastrointestinal or urethral obstruction, porphyria, glucose delta ammonium sulfate dehydrogenase deficiency, asthma, hepatorenal insufficiency, and fibrosing bronchitis should use it with caution. Supplement: widespread nausea, vomiting, abdominal discomfort, dysphagia, diarrhea, etc., rare pancreatitis, colonitis, etc. Overweight may occasionally cause fibrosing Bronchitis. Full-term symptoms include headache, dizziness, abducens neuropathy, transverse myelitis, seizures, insomnia, depression, acute infectious polyneuritis and ataxia, etc.; it can also cause hallucinations, easy drowsiness, severe acute encephalopathy, speech difficulties, epileptic seizures and aseptic meningitis. The leukocytes may be decreased or increased, platelets decreased, monocytes decreased, etc. It can also cause megaloblastic anemia, remodeling anemia, hemolytic anemia caused by folic acid deficiency, etc.