What should I do if my free prostate-specific antigen is too high?

High free prostate-specific antigen refers to an abnormal state of prostate-specific antigen indicators, which is also a common physical disease in men. When men have high free prostate-specific antigen, it is easy to cause some physical diseases or complications, and it is also easy to affect the health of the body. It can be treated through examination.

What should I do if my free prostate-specific antigen is too high?

The free prostate-specific antigen index needs to be combined with the total prostate-specific antigen index to play a role in judging the possibility of prostate tumor. Analyzing the free prostate-specific antigen index alone cannot produce a reliable result or have practical clinical significance.

If the total PSA is less than 4ng/ml, or exceeds 10ng/ml, the reference value of the free PSA is not very meaningful. At this time, even if the free PSA index is too high or too low, it cannot indicate anything. If the total PSA index is less than 4ng/ml, the possibility of prostate cancer is basically ruled out. If it exceeds 10ng/ml, the possibility of prostate cancer is very high. In addition, if the total PSA index is within the range of 4-10ng/ml, this is a gray area, and the free PSA needs to be referred to at this time. The smaller the ratio of the two, the greater the possibility of prostate cancer.

It is generally believed that if the free PSA value is greater than 0.16 compared to the total PSA, the possibility of malignancy is relatively small.

PSA is tissue-specific and exists only in the cytoplasm of human prostate acinar and ductal epithelial cells. It is not expressed in other cells. However, it has no tumor specificity. Prostatitis, benign prostatic hyperplasia, and prostate cancer can all lead to an increase in total PSA levels (free PSA plus composite PSA). Prostate cancer has surpassed skin cancer to become the most common cancer in North American men and ranks second among cancer-related deaths. PSA will increase in most clinically significant prostate cancers and is also its most important early detection indicator. Although PSA is the most commonly used method for detecting prostate cancer, benign prostatic hyperplasia and prostatitis can also show PSA-positive results. One way to solve this problem is to detect free prostate-specific antigen.