Will penile nodules heal on their own?

Penile nodules are a common male disease, and also a disease that will have a dual impact on male sexual function and fertility. Once penile nodules occur, it is unlikely that they will heal naturally. Patients need to receive active treatment according to the cause of the disease before they can recover. Below, we will introduce the causes, clinical manifestations and treatment methods of penile nodules.

The etiology of this disease is still unclear, but it is suspected to be related to chronic injury and inflammation of the penis, vitamin E deficiency, genetic factors, sexually transmitted diseases, and autoimmune reactions.

2. Clinical manifestations

The severity of Peyronie's disease can be mild, moderate or severe, and symptoms can develop gradually or overnight. The main clinical symptoms include the following:

1. Local induration

Painless hard plaques appear on the penis. The nodules are mostly located on the back of the penis. Small ones are the size of rice grains, while large ones can spread to the entire back of the penis. They are round, cord-like or plaque-like, hard in texture, fixed and immobile, and the skin and subcutaneous tissue are usually not affected.

2. Penile curvature

Most patients only experience penile curvature during erection. A lump on the upper side of the penis will cause the penis to bend upward, while a lump on the lower side of the penis will cause the penis to bend downward. The curvature is usually 30°-120°.

Some patients may have lumps on both the upper and lower sides of the penis, shortening and deforming the penis.

4. Erection pain

The penis feels uncomfortable or painful when it is erect. There is usually no pain when it is not erect, and some people only feel pain during sexual intercourse.

5. Erectile dysfunction

6. Difficulty in sexual intercourse

Due to pain and curvature during erection, some patients have erectile dysfunction and difficulty or failure in sexual intercourse due to huge plaques affecting the blood supply to the corpus cavernosum.

1. Drug treatment

(1) Local injection of collagenase is effective for mild symptoms, and local injection of verapamil into the plaque may also be effective.

(2) Oral administration of large doses of vitamins, along with oral administration of diethylstilbestrol and potassium iodide can be used as adjuvant therapy.

(3) Anti-fibrotic drugs, such as potassium aminobenzoate.

(4) Drugs that inhibit connective tissue proliferation, such as hydrocortisone acetate, dexamethasone, procaine, etc., are effective for early lesions.

2. Physical therapy

Diathermy or ultraviolet radiation can be used as adjunctive therapy to improve symptoms.

3.Surgery

The purpose of surgical treatment is to prevent the penis from bending during erection and remove the nodules. Currently, the commonly used surgical methods include surgical nodule removal and prosthesis implantation, but the surgical effect is not very ideal and the disease is prone to recurrence after surgery.