What is chancroid? Causes of chancroid

Chancroid is actually a sexually transmitted disease. Since most cases are transmitted through sexual contact, this reminds us that we must pay attention to the health and hygiene of our sexual lives, put an end to promiscuous and unclean sexual behavior, and also pay attention to scientific treatment.

1. Chancroid is mostly transmitted through sexual contact. During sexual intercourse, the disease is transmitted through direct contact with the patient's open wound secretions and ulcer pus. Although some female patients' wounds have healed, they are still carriers, and sexual intercourse with these asymptomatic latent patients can also transmit the disease. Generally, contact with patients will not transmit chancroid, but it can also be infected by contacting the patient's wound without paying attention to disinfection and isolation. Due to the emergence of various sexual lifestyles in modern times, the disease can also occur near the anus, hands, eyelids, lips and breasts.

2. After Haemophilus ducreyi invades the body, it causes single or multiple painful necrotic ulcers at the contact sites of the reproductive organs. The incubation period is generally 1-6 days after sexual intercourse. Inflammatory erythema, papules, blisters or small abscesses occur locally in the infection, surrounded by inflammatory erythema, and soon rupture to form ulcers. The ulcers are round, oval or irregular in shape, with a diameter of 1-2 cm. The base of the ulcer is a granulomatous tissue with rich blood vessels, which is tender and easy to bleed. The base is not as hard as a chancre, and there is a burning sensation when the ulcer comes into contact with urine, which is a typical symptom of female patients. Initially, the ulcers are single, but because they can be self-inoculated, they are often arranged in satellites around the primary ulcer, ranging from small rapeseed-like to large fingernail-like. Sometimes they fuse together to form large ulcers, and sometimes they quickly destroy large tissues, causing vulvar deformities and a foul odor.

3. If there are no complications, ulcers usually heal themselves in 3-8 weeks, leaving shallow scars. The mechanism of self-healing of this disease is generally believed to be that when infected with Haemophilus ducreyi, the body can produce non-specific immune responses and specific immune responses. The skin and mucous membranes, as the body's natural barriers, have a certain bactericidal effect. Macrophages have a phagocytic effect on cells. Tonic bodies, lysozymes and properdin in body fluids can inhibit bacteria, kill bacteria or enhance the phagocytic effect of phagocytic cells. Humoral immunity and cellular immune responses may have a certain effect on killing Haemophilus ducreyi. Therefore, many patients can heal themselves without any treatment.