In life, some netizens will have joint stiffness and pain in the early stage. They should go to the hospital for examination as soon as possible, because these are the early symptoms of rheumatoid arthritis. In addition to these symptoms, what are the other early clinical symptoms of rheumatoid arthritis? 1. Its outstanding clinical manifestations are: Recurrent, symmetrical, multiple facet arthritis, most commonly affecting the joints of the hands, wrists, and toes. 2. Early performance In the early stage, symptoms include redness, swelling, heat, pain and functional impairment. In the late stage, the joints may become stiff and deformed to varying degrees, and there may be bone and skeletal muscle atrophy. It is a disease with a high disability rate. 3. Pathology From the perspective of pathological changes, rheumatoid arthritis is a widespread inflammatory disease that primarily affects the synovium of the joints (and later may affect the joint cartilage, bone tissue, ligaments and tendons), followed by the synovium, heart, lungs and eyes and other connective tissues. Therefore, in addition to the above symptoms of arthritis, patients may also have other systemic manifestations, such as fever, fatigue, weight loss, subcutaneous nodules, pericarditis, pleurisy, peripheral neuropathy, eye lesions, arteritis, etc. 4. Condition and course of disease The condition and course of the disease vary from individual to individual, ranging from transient, mild oligoarthritis to rapidly progressive polyarthritis. The most commonly affected joints are the proximal interphalangeal joints, metacarpophalangeal joints, wrists, elbows, shoulders, knees, and toe joints; the cervical spine, temporomandibular joints, sterno-clavicular joints, and acromioclavicular joints may also be affected, with limited mobility; hip joints are rarely affected. Arthritis often presents with symmetrical, persistent swelling and tenderness, and morning stiffness often lasts for more than 1 hour. The most common joint deformities are wrist and elbow ankylosis, subluxation of the metacarpophalangeal joints, ulnar deviation of the fingers, and a "swan neck" and button-like appearance. Severely ill patients have fibrous or bony ankylosing joints, and due to atrophy and spasm of the muscles around the joints, they lose their joint function, making them unable to take care of themselves. In addition to joint symptoms, there may also be damage to the joints or internal organs, such as rheumatoid nodules, heart, lung, kidney, peripheral nerves and eyes. |
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