Understanding Male Breast Hyperplasia

Male breast hyperplasia is a common clinical problem. Patients are most concerned about whether it causes discomfort to the body, affects the appearance, or suspects it is cancer. However, many male friends do not know much about this disease. Some male friends do not even know that they have this disease. So today we will ask authoritative experts to help you understand male breast hyperplasia.

It is generally believed that except for three situations in a man's life (transient gynecomastia in newborns, breast enlargement during adolescence, and occasional gynecomastia in older men), the ability to touch breast tissue is considered abnormal.

Symptoms and signs

Men have palpable breast tissue on one or both sides, which is disc-shaped or diffusely enlarged, sometimes accompanied by enlarged nipples and areolas. Local pain or tenderness may be felt, and a small amount of white secretions may be seen when the nipples are squeezed. Pathological gynecomastia caused by organic diseases also has the clinical manifestations of the primary disease.

Medication

1. Dihydrotestosterone enanthate 200mg, intramuscular injection once every 3 to 4 weeks. One group reported that after 3 months of treatment, the breast shrank by 67% to 78%. During the treatment period, plasma DHT increased, and the levels of LH, FSH, T and E2 were suppressed. They returned to normal after 2 months of discontinuation of the drug. There was no recurrence of the disease after 6 to 15 months of follow-up observation. At present, it is still in the trial stage, and no DHT preparation is available on the market.

2. Tamoxifen (tamoxifen) can bind to the estrogen receptors in the target tissue and block the effect of estrogen. The usual dose is 20 mg/d, taken orally in divided doses. Some people report that the breasts shrink significantly after taking the drug for one month. If the effect is not significant, the dose can be appropriately increased.

3. Clomiphene The mechanism of action is similar to that of tamoxifen. Oral administration of 50-100 mg/d has therapeutic effects in about 70% of patients to varying degrees.

4. Testosterone lactone inhibits aromatase and blocks the conversion of testosterone to E2 in the periphery. Some people report that 450 mg/d, taken orally in divided doses, has significant efficacy. No adverse reactions were found. After taking the drug, the ?4A level increased significantly, T, DHEA and E1 increased slightly, the ?4A/E1 ratio increased, and there was no significant change in the levels of LH, PRL and E2.

5. Chinese medicine Traditional Chinese medicine believes that male breast development is caused by liver qi stagnation and phlegm and dampness in the body. The treatment method should be to use drugs that soothe the liver and regulate qi, strengthen the spleen and resolve phlegm. Some people report that Xiaoyao Powder can be effective up to 90%, but unfortunately there is a lack of comparison.

6. Mammoplasty Due to the irreversibility of long-term delayed gynecomastia, mammoplasty is still an important means of treating this disease. Generally, a circum-areolar approach is used to remove the subareolar breast tissue.

Diet and Health

Eat light food and pay attention to eating habits.

Preventive care

Stop taking and using drugs that may cause male breast development. If necessary, use it under the guidance of a regular hospital doctor and have regular checkups.

Pathological etiology

The growth of female breasts depends on the action of estrogen. Giving estrogen to men can also lead to breast development, and it cannot be distinguished from male breast development caused by other reasons in histology. Therefore, it can be considered that all male breast development is caused by increased estrogen secretion or decreased androgen/estrogen ratio. Excessive estrogen is the main cause of male breast development. Giving men exogenous estrogen preparations, such as estrogen treatment for prostate cancer patients, long-term use of estrogen in transgender men, and excessive estrogen secretion from adrenal or testicular tumors can all lead to breast hyperplasia.

The above is the relevant article about male breast hyperplasia. After reading the above article, I believe everyone has some understanding of this disease, so that they can ensure that they can detect the disease as soon as possible and have a good treatment.