What does a male chromosome abnormality cause?

There are many kinds of diseases that people suffer from, and the causes of each disease vary. However, some problems related to genetic diseases may be very serious. This means that the individual's development and growth process is imperfect, and some organs may have functional disorders. The body's defense capabilities are insufficient, and normal human metabolic reactions cannot be completed, affecting normal life. This is similar to the problem of male chromosomal abnormalities. How should it be solved?

Chromosomes are the basic substances that make up the cell nucleus and are the carriers of genes. Chromosome abnormalities are also called chromosome dysgenesis. Chinese-American Jiang Youxing (1956) found that humans have 46 chromosomes, and Caspersson et al. (1970) published the first human chromosome banding photos. Chromosomes are the carriers of genes, and chromosomal diseases are chromosomal abnormalities, which lead to abnormal gene expression and abnormal development of the body. The pathogenesis of chromosomal aberrations is unknown, and it may be caused by the non-separation of chromosomes in the late stage of cell division or the breakage and reconnection of chromosomes under the influence of various factors inside and outside the body.

Normal people have 46 chromosomes in their somatic cells, which have certain shapes and structures. Abnormalities in the shape, structure or number of chromosomes are called chromosomal abnormalities, and diseases caused by chromosomal abnormalities are called chromosomal diseases. More than 100 types of chromosomal diseases have been discovered, which can often cause miscarriage, congenital idiocy, congenital multiple malformations, and cancer in clinical practice. The incidence of chromosomal abnormalities is not uncommon, reaching 0.5%~0.7% in the general newborn population. For example, based on the average number of 3,000 newborns born in our hospital each year, there may be 15~20 cases of chromosomal abnormalities. In the case of early spontaneous abortion, about 50%~60% are caused by chromosomal abnormalities. Common causes of chromosomal abnormalities include ionizing radiation, chemical exposure, microbial infection, and genetics. The purpose of clinical chromosomal examination is to detect chromosomal abnormalities and diagnose diseases caused by chromosomal abnormalities.

It may cause some problems, similar to male infertility problems. Pregnant women who have habitual miscarriages and premature fetal death may also be caused by male chromosomal abnormalities. Therefore, pay attention to various physical examination information before marriage. Once these problems occur in unborn children, it will bring great harm to the family, because some newborns may have intellectual disabilities due to these reasons.