Treatment of lupus nephritis in men

I believe everyone knows the importance of kidneys to male friends. If there is a problem with the kidneys of male friends, it is not only easy to feel uncomfortable but also may affect excretion. Kidney disease may even threaten our lives. Therefore, we recommend that male friends must pay attention to protecting their kidneys in daily life. Lupus nephritis is a type of kidney disease. Below we introduce the treatment methods of male lupus nephritis.

Lupus nephritis refers to a disease in which systemic lupus erythematosus (SLE) is combined with immune damage of different pathological types in both kidneys, accompanied by obvious clinical manifestations of renal damage. Its onset is related to immune abnormalities such as immune complex formation, immune cells and cytokines. In addition to the systemic manifestations of SLE, the main clinical manifestations are hematuria, proteinuria, renal insufficiency, etc. The pathological classification of lupus nephritis is of great value in judging the activity and prognosis of the disease and formulating treatment plans. The treatment plan should be individualized according to the severity of the disease.

1. Treatment principles

SLE is still a disease of unknown cause. The main purpose of treatment is to control the activity of LN, protect kidney function, and delay the process of renal tissue fibrosis.

2. Mild SLE and lupus nephritis

For patients with normal or stable target organ function, nonsteroidal anti-inflammatory drugs or anti-malarial drugs can be used as appropriate. Medium or small doses of glucocorticoids (such as prednisone 20-40 mg/d) can be used for a short period of time, and immunosuppressants can be added when necessary.

3. Severe SLE and lupus nephritis

Patients with obvious damage to important target organs, persistent glomerulonephritis, rapidly progressive glomerulonephritis, and nephrotic syndrome should be given standard hormone therapy (prednisone 1 mg/kg/d) and immunosuppressant therapy. Patients with acute life-threatening severe lupus should be given hormone shock therapy (methylprednisolone 0.5-1.0 g/d). When the above methods are ineffective or the condition is severe, plasma exchange therapy can be considered. Patients with acute severe renal insufficiency, severe hypervolemia, and heart failure should undergo emergency dialysis to help them get through the critical period.

4. Treatment at the terminal stage

End-stage lupus nephritis is treated as chronic renal failure.

In the above article, we introduced the importance of kidneys to male friends. We recommend that male friends should protect their kidneys in their daily lives. The above article introduces in detail the treatment methods for male lupus nephritis.