Treatment of prostate hyperplasia

Prostatic hyperplasia is a common disease in men. Many men have suffered from it, but most of them are middle-aged and elderly patients. There are many reasons for prostatic hyperplasia, but most people don't know about it. So, what is the treatment for prostatic hyperplasia? This is what many men need to know and want to know.

In fact, there are many treatments for prostate hyperplasia in today's life, so friends with prostate hyperplasia should not be afraid or anxious, because many methods can cure prostate hyperplasia, but it is better for our prostate hyperplasia patients to receive treatment as early as possible. So, in response to this phenomenon, let's talk about the treatment methods for prostate hyperplasia.

The harmfulness of prostatic hyperplasia lies in the pathological and physiological changes caused by lower urinary tract obstruction. The pathological individual differences are very large, and not all of them are progressive. Some lesions will no longer develop after reaching a certain degree, so even if mild obstruction symptoms occur, surgery is not always required.

1. Waiting and Observation

If the symptoms are mild and the IPSS score is below 7, the condition can be observed and no treatment is required.

2. Drug treatment

(1) 5α-reductase inhibitors Studies have shown that 5α-reductase is an important enzyme for the conversion of testosterone to dihydrotestosterone. Dihydrotestosterone plays a certain role in prostate hyperplasia, so the use of 5α-reductase inhibitors can inhibit hyperplasia to a certain extent.

(2) α-receptor blockers Caine (1975) confirmed that there are more α-receptors in the prostate and bladder neck, and the use of pheniramine has an efficacy of 80%. It is currently believed that this type of drug can improve urinary tract dynamic obstruction, reduce resistance and improve symptoms. Commonly used drugs include Gotrin, Santa, and Haro.

(3) The most widely used anti-androgen drugs are progesterone drugs. They can inhibit the cellular binding and nuclear uptake of androgens, or inhibit 5α-reductase and interfere with the formation of dihydrotestosterone. Progesterone drugs include megestrol acetate, cyproterone acetate, chlormadinone acetate, and progesterone caproate. Flubutamide is a non-steroidal anti-androgen drug that can also interfere with the cellular uptake and nuclear binding of androgens. After using anti-androgen drugs for a period of time, symptoms and urine flow rate can be improved, residual urine can be reduced, and the prostate can be reduced. However, after stopping the drug, the prostate will enlarge again and symptoms will recur. In recent years, it has been found that this type of drug can increase blood viscosity and increase the incidence of cardiovascular and cerebrovascular embolism. Luteinizing hormone-releasing hormone analogs have a highly selective effect on the pituitary gland, causing it to release LH and FSH. Long-term use can exhaust this function of the pituitary gland, reduce the ability of the testicles to produce testosterone, or even make it impossible to produce testosterone, thus achieving the effect of drug removal of the testes.

In summary, a comprehensive assessment of the condition should be made before drug treatment, and the side effects of the drugs and the possibility of long-term medication should also be fully considered. Long-term follow-up should be conducted to observe the effects of drug treatment, and urodynamic tests should be performed regularly to avoid delaying the timing of surgery.

To summarize, the current medical treatment for prostate hyperplasia is generally based on drug therapy, so our patients should be examined in time, and after confirming the cause and condition, they should start drug treatment as soon as possible. Although drug treatment is very effective for prostate hyperplasia, due to the efficacy of the drug, it still takes some time to completely cure prostate hyperplasia.