The main causes of prostatitis

Prostatitis can be said to be a disease that male friends often encounter. Suffering from prostatitis will cause patients to have systemic symptoms such as chills, fever, fatigue and weakness. So once discovered, it is necessary to actively treat it. So why do people suffer from prostatitis? First of all, it is due to unhealthy living habits, and also due to some viruses, infections and other reasons.

Prostatitis refers to a prostate disease caused by a variety of complex reasons, with urethral irritation symptoms and chronic pelvic pain as the main clinical manifestations. Prostatitis is a common disease in urology, and ranks first among male patients under 50 years old in urology. Although the incidence of prostatitis is very high, its cause is still not very clear, especially non-bacterial prostatitis, so its treatment focuses on improving symptoms. In 1995, the National Institutes of Health (NIH) of the United States developed a new classification method for prostatitis, Type I: equivalent to acute bacterial prostatitis in the traditional classification method, Type II: equivalent to chronic bacterial prostatitis in the traditional classification method, Type III: chronic prostatitis/chronic pelvic pain syndrome, Type IV: asymptomatic prostatitis. Among them, non-bacterial prostatitis is far more common than bacterial prostatitis.

Causes

Only a few patients have an acute history, and most of them present with chronic, recurrent symptoms. The main pathogenic factors of type I and type II prostatitis are pathogenic infection, mainly Escherichia coli, Klebsiella, Proteus and Pseudomonas aeruginosa. Pathogens invade the prostate with urine, causing infection. Pathological anatomy confirms that prostatitis lesions are generally limited to the peripheral zone, where the glandular duct opens in the posterior urethra in the opposite direction of the vertical line of urine flow, which is easy to cause urine reflux, while the glandular ducts in the central zone and transitional zone are consistent with the direction of urine flow, and are not easy to be infected.

The prostate has as many as 15 to 30 ducts opening on both sides of the seminal colliculus, and the prostate epithelium has a strong secretory function. The gland is small but the secretory function is strong, and the ducts are narrow, which causes the prostate to be compressed and blocked under the influence of various factors, which can easily cause congestion and secretion accumulation, thus creating conditions for infection. This is also the histological basis for the easy recurrence of prostatitis. Excessive sexual activity, excessive masturbation, long-term sitting, riding a bicycle, riding a horse, alcoholism, excessive spicy food, colds, etc. can all become its inducing factors.

The pathogenesis of type III prostatitis is unknown, and its etiology is very complex and widely debated. Most scholars believe that its main causes may be pathogen infection, urination dysfunction, psychological factors, neuroendocrine factors, abnormal immune response, oxidative stress theory, lower urinary tract epithelial dysfunction, etc. Type IV prostatitis lacks research on its related pathogenesis, and may have some of the same causes and mechanisms as type III.

Urine reflux in the prostate may be of great significance to the occurrence of various types of prostatitis. Recent studies have found that uric acid in urine not only stimulates the prostate, but can also precipitate into stones, block the gland ducts, and serve as a shelter for bacteria. These findings can explain that prostatitis syndrome is actually a common manifestation of multiple diseases, and the clinical manifestations are complex and varied, which can produce various complications or resolve on their own.