How to treat high estradiol in men? Men, friends must pay attention.

There are many reasons for the increase of male estradiol, which is often manifested as male feminization, testicular tumors, liver cirrhosis and other symptoms. It has a particularly great impact on men's health. So how should male friends treat high estradiol? In fact, finding the cause and treating the symptoms is the key.

Estradiol E2: Normal range: Male: 50-200pmol/L; Female: 94-433pmol/L in follicular phase, 499-1580pmol/L in luteal phase. Test introduction: Estradiol (E2) is mainly produced by ovarian follicles, corpus luteum and placenta during pregnancy. Clinical significance: Female ovulation period is 704-1580pmol/L, menopause period is 40-100pmol/L. Increase: seen in feminization of children, estrogen-producing tumors, gynecomastia, decompensated liver cirrhosis, and adrenal cortical hyperplasia. Decrease: seen in Turner syndrome, primary and secondary sexual dysfunction. Progesterone p: [Normal range] Male: Adult <3.2nmol/L Female: 0.6-1.0 nmol/L in the follicular phase, 1.0-11.2 nmol/L in the ovulatory phase, 20.8-103.0 nmol/L after ovulation [Clinical significance] Increased: congenital adrenal cortical hyperplasia (21β-hydroxylated ume deficiency, 17β-hydroxylated ume deficiency and 11β-hydroxylated ume deficiency, etc.), ovarian tumor, hydatidiform mole.

Reduce: miscarriage, amenorrhea-galactorrhea syndrome, etc.

Life Tips:

Estradiol, the most active estrogen in men, is produced in small amounts in the testicles and adrenal glands, while most of it is converted from the androgen testosterone by peripheral tissues such as skin follicles, fat, and nerves. An adult male can produce 30 to 40 micrograms of estradiol every day. The standard is: Men: 29-132pmol/l. Excessive estradiol in men can cause feminization. High levels of estradiol and testosterone indicate a strong sexual desire. If the levels are not too high, the impact will not be significant. If the levels are too high, it indicates the risk of testicular disease.

Generally, if it is in the early stage of development, this situation may occur temporarily, and it can usually be observed for a period of time and then rechecked. If it is past the development period or in the late stage of development, it is necessary to find out the cause of the increase in estradiol in order to treat it accordingly. Is it recommended to pay attention to whether the liver function is normal? Because male estrogen is inactivated in the liver, if there is a large amount of drinking and the use of drugs that affect liver function, or if there is liver disease, there is a possibility of this. In addition, have you recently consumed some foods or drugs containing estrogen (such as some ripened vegetables and fruits that contain estrogen). It is recommended to decide the treatment method according to the specific situation. If necessary, oral androgens can be used to solve the problem, but it must be used under the guidance of a doctor to avoid adverse reactions.