Have you heard of vasospasm? I believe that most of the male netizens here may not have heard of such a disease, but have only heard of stomach spasm. In fact, not having heard of it does not mean that this disease does not exist. In clinical practice, for example, cerebral vasospasm will cause patients to have severe pain and other symptoms, so it must be treated in time. 1. Etiology and treatment Find the cause and carry out active treatment, especially strengthening the prevention and treatment of atherosclerosis. 2. Drug treatment 1. Early use of cerebral vasodilators and volume expanders can significantly reduce and terminate TIA clinical attacks. Betamine 20 mg added to 500 ml of 5% glucose, or low molecular weight dextran or 706 generation plasma 500 ml intravenous drip can be used. Vinaroton, Sibelium, etc. may also have a certain effect. 2. Antiplatelet aggregation agents can reduce the occurrence of microemboli. For patients without ulcer disease or hemorrhagic diseases, aspirin is often used for treatment, ranging from 50mg to 300mg per day. Most people think that a smaller dose is appropriate, and the dose can be reduced if taken for a long time. Dipyridamole (25mg 3 times a day) can be used in combination with aspirin to have a synergistic effect and can reduce the dose of aspirin. If the patient is not suitable for aspirin or the aspirin effect is not ideal, ticlopidine (Ticlopidine 200-250mg 1-2 times a day) or ticlid 250mg, once a day) can be used instead. During treatment, attention should be paid to strengthening the prevention and treatment of toxic side effects such as bleeding. 3. Anticoagulant therapy For patients with frequent attacks, severe and progressively worsening conditions and no obvious contraindications to anticoagulant therapy, early anticoagulant therapy is of positive significance in reducing attacks and preventing cerebral infarction. Heparin 12500U is commonly added to 5% glucose saline for slow intravenous drip. At the same time, 300mg of new dicoumarin or 100-200mg of dicoumarin or 4-6mg of warfarin can be taken orally on the first day. Check the prothrombin time and activity every day, and measure it once a week after stabilization to adjust the oral dosage. The intravenous coagulation time is required to be maintained at 20-30 minutes and the prothrombin activity at 15-25%. The maintenance dose is 150-225 mg of cypermethrin, 25-75 mg of cypermethrin or 2-4 mg of warfarin. During treatment, attention should be paid to preventing and treating bleeding complications. The dose should be gradually reduced after discontinuation of the drug to avoid a "rebound effect". Since this treatment is difficult to control the dosage and has many bleeding complications, it is rarely used in China. |
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