Many people will find that they have bumps around their genitals in their daily lives. This is a manifestation of genital herpes. Genital herpes can be divided into several types. Some are simply pathological, and some are physiological factors, such as sexual contact through sexually transmitted diseases and misusing other people's personal items. These are all causes of genital infection, so everyone needs to pay attention to it in daily life. Pathological etiology Pathogen: Herpes simplex virus (HSV). HSV is a type of herpes virus, a relatively large DNA virus with a diameter of 150 to 200 nm. The central spherical region is a core composed of double-stranded DNA, which is covered with a three-dimensional symmetrical icosahedron composed of 162 capsid particles, surrounded by a lipid-containing envelope. HSV can be divided into two antigenic types, namely HSV-1 and HSV-2. More than 99% of HSV-1 infections occur in the mouth, pharynx, nose, eyes and skin, while HSV-2 infections are common in GH. According to statistics, 90% of GH pathogens are HSV-2 and 10% are HSV-1. The two are different in many aspects, and their differences are shown in Table 1. HSV is cold-resistant and heat-sensitive. It can be quickly inactivated in water at 50-52℃, can survive for weeks at 4℃, and can survive for months at -70℃. However, in a dry environment, even high temperatures can extend its survival time. HSV is sensitive to commonly used disinfectants, and can be inactivated by 0.5% formaldehyde solution, 1% Lysol solution or soapy water. Disease Diagnosis GH must be distinguished from the following diseases. 1. Fixed drug eruption: There is a history of drug allergy and a history of medication before the rash. The site of each outbreak is fixed and not limited to the vulva. There are also damages to other skin and mucous membrane junctions. The skin damage is mainly dark erythema with thick-walled blisters or large blisters. 2. Behcet syndrome may first present as oral or genital ulcers with a positive acupuncture test, and may later be accompanied by iridocyclitis and erythema nodosum of the limbs. 3. Syphilitic chancre: The incubation period is 2 to 4 weeks, with local nodules and ulcers, no spontaneous symptoms, and positive reactions to Treponema albicans and syphilis serum. 4. Chancroid: There is a history of sexual promiscuity 2 to 5 days before the onset of the disease. The lesions are ulcers in the vulva with a soft base, accompanied by pain and tenderness. The unilateral inguinal lymph nodes are enlarged and tender. Ulcers may form and discharge pus, and Haemophilus Ducrey may be detected. |
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