What disease is the small granulation in the coronal sulcus of the glans penis?

The male penis is a reproductive organ, so it is very important to men. Of course, the male penis is also one of the necessary tools for sexual life. If there is a contagious disease here, not only the man himself will be injured, but also his sexual partner. So in daily life, men must pay more attention to their penis and glans. So, what is the disease of a circle of small granulations in the glans coronal groove?

Condyloma acuminatum is a sexually transmitted disease caused by human papillomavirus (HPV) infection, with the main manifestation being proliferative lesions in the anal and genital areas. It mostly occurs in young and middle-aged people aged 18 to 50. The disease occurs after a latent period of about half a month to eight months, with an average of three months. This disease is relatively common and is mainly transmitted through sexual contact.

Causes and transmission

There are different subtypes of HPV. The most common HPVs that cause condyloma acuminatum are HPV 6 and 11. HPV can easily survive and reproduce in the warm and humid environment of the human body, so the external genitalia and perianal area are the most susceptible areas for infection. There are several ways of transmission:

1. Sexual contact transmission

It is the main route of transmission. Therefore, this disease is prone to occur in people with disordered sexual relationships.

2. Indirect contact infection

A small number of patients may become ill due to contact with items used by patients, such as underwear, bath towels, bathtubs, toilet seats, etc.

3. Mother-to-child transmission

Laryngeal papilloma of the infant occurs through transmission through the birth canal during delivery.

Clinical manifestations

The incubation period is 1 to 8 months, with an average of 3 months, and it mainly occurs in sexually active people.

1. Typical condyloma acuminatum

Genital and perianal areas are the most common sites. In men, it is more common in the foreskin, frenulum, coronal sulcus, glans penis, urethral orifice, penis body, perianal area, rectum and scrotum. In women, it is more common in the labia majora and minora, posterior symphysis, vestibule, clitoris, cervix and perianal area. Occasionally, it can be seen in areas other than the genitals and perianal area, such as the axilla, umbilical fossa, oral cavity, breasts and between toes. Female vaginitis and male prepuce hyperplasia are the factors that promote the occurrence of condyloma acuminatum.

The lesions are initially small, light red papules, which gradually increase in size and number, distributed singly or in clusters, moist and soft, with an uneven surface, and are papillary, cockscomb-shaped or cauliflower-like protrusions. They are red or dirty gray. There is often a pedicle at the root, and erosion and exudation are prone to occur, and they bleed easily when touched. There is often accumulation of purulent secretions between the cracks of skin lesions, resulting in a foul odor, and secondary infection may occur due to scratching. This disease is often asymptomatic, and some patients may experience foreign body sensation, pain, itching or pain during sexual intercourse. Condylomas in the rectum may cause pain, blood in the stool, and a feeling of tenesmus.

2. HPV subclinical infection

HPV infection is clinically invisible to the naked eye, but evidence of HPV infection can be found by acetowhitening test (local whitening after smearing or wet compressing with 5% acetic acid solution), tissue pathology or nucleic acid detection technology.

3. Relationship with tumors

A large amount of epidemiological data shows that HPV infection (mainly high-risk HPV, such as HPV-16 and HPV-18) is closely related to the occurrence of genital cancers, such as cervical cancer and penile cancer.

The prognosis is generally good after treatment. However, recurrence is possible regardless of the treatment method.