What are anti-sperm antibodies?

In life, some couples have infertility problems, which may be caused by anti-sperm antibodies. As the name suggests, anti-sperm antibodies appear in the body to resist sperm, which will hinder conception. This happens to both men and women.

Anti-sperm antibodies (AsAb) are a complex pathological product that can occur in both men and women, and the exact cause is not yet fully understood. Male sperm and seminal plasma are both specific antigens for women. After contact with blood, both men and women can induce an immune response and produce corresponding antibodies, which prevent sperm from combining with eggs and cause infertility.

Basic Introduction

The above-mentioned situations are sperm immune infertility. The female reproductive tract, especially the macrophages in the uterus, will identify sperm as "foreign matter" and devour them when AsAb is positive. Under normal circumstances, there is no AsAb in women's blood, but under the above-mentioned special circumstances, the female body "defends itself" against the antigen of sperm and semen, and "family members do not recognize family members", causing the immune system to produce antibodies. In men, it is their own "self-defense" that causes their own immune system to produce antibodies, resulting in "self-destruction", making it difficult for sperm to survive.

Treatment

Antisperm antibodies are a complex pathological product that can affect both men and women, and the exact cause is not yet fully understood. Male sperm and seminal plasma are specific antigens for women. After contact with blood, both men and women can cause immune reactions and produce corresponding antibodies, which prevent sperm from combining with eggs and cause infertility. Female patients with positive antisperm often have reproductive system inflammations such as endometritis, vaginitis, and salpingitis before the onset of the disease. For this situation, lymphatic immunotherapy can be used for treatment.