What are the causes of male infertility?

The occurrence of diseases does not discriminate among people. There are too many types of diseases nowadays, but the problem that worries family members and newly married couples the most is infertility and the problem of having a baby. So what are the causes of male infertility? Friends who want to know more can read the following introduction to the causes of male infertility, which may be of some help to you.

Causes

The causes of this disease are complex, and many diseases or factors can lead to male infertility. According to the results of semen examination, it can be classified into azoospermia, severe oligospermia, oligospermia, infertility with normal sperm count, polyspermia, and sperm insufficiency.

Common causes of male infertility include:

1. Common chromosomal abnormalities include male pseudohermaphroditism, Klinefelter syndrome and XYY syndrome. Chromosomal abnormalities such as 46XY/47XXY can cause testicular spermatogenesis disorders.

2. Endocrine diseases: Hypothalamic dysfunction, such as Kallmann syndrome, is mainly caused by gonadotropin-releasing hormone deficiency; pituitary dysfunction, such as selective luteinizing hormone (LH) deficiency and follicular gonadotropin (FSH) deficiency, hyperprolactinemia, etc. Adrenal hyperplasia can inhibit the pituitary secretion of FSH and LH, leading to infertility.

3. Reproductive tract infections such as prostatitis, epididymitis, orchitis, and urethritis. Severe cases may affect male fertility.

4. Congenital and acquired obstruction of the vas deferens can affect sperm transport and cause infertility.

5. Abnormal testicular spermatogenesis: Cryptorchidism, microtestis, atestis, viral orchitis, varicocele, toxins, magnetic fields, high fever and trauma and other physical and chemical factors can cause testicular spermatogenesis disorders.

6. Sperm structure abnormalities and seminal plasma abnormalities can affect sperm motility, capacitation, and acrosome reaction.

7. Immune infertility: Anti-sperm antibodies produced by men themselves and anti-sperm antibodies produced by women can affect sperm motility and its ability to penetrate eggs.

8. Male sexual dysfunction Erectile dysfunction, premature ejaculation, anejaculation and retrograde ejaculation can all cause male infertility.

9. Drug factors: Common ones include cimetidine, sulfasalazine, triptolide, spironolactone, nitrofurantoin, niridazole, colchicine, various hormone drugs and cancer chemotherapy drugs such as certain alkyl compounds, which can often cause temporary or permanent damage to sperm production.

For those male infertility patients, what they want to know most is the cause of infertility. Where does the root cause occur? If the cause is understood, the treatment can be targeted and there will be a possibility of improvement. So please take some time to read the article to introduce the causes of male infertility. After reading it, you will definitely have some inspiration.