26 What should I do if a man has inherited high blood pressure and his blood pressure is 150?

The condition of hypertension is not unfamiliar at all, because everyone knows that hypertension is actually a kind of elevated blood pressure, which causes minor problems in the patient's body. Generally, hypertension often occurs in middle-aged and elderly people, and rarely occurs in children. However, some young people have hypertension, and at this time, we must follow the principles of prevention and treatment.

Prevention principles

1. Monitor blood pressure regularly, at least once a year under normal circumstances.

2. Limit salt intake and supplement potassium. Gradually control the daily salt intake to 5 grams, and eat more fruits and vegetables rich in potassium (such as bananas, walnuts, lotus seeds, coriander, amaranth, spinach, etc.).

3. Prevent overweight and obesity.

4. Quit smoking and limit alcohol intake.

Genetic factors

The genetic factors of primary hypertension, that is, the family relationship, have been confirmed by many years of medical practice. The familial tendency of patients with hypertension is established in early life. If both parents suffer from hypertension, the incidence rate of their children is 46%; if one parent suffers from hypertension, the incidence rate of their children is 28%; if the parents have normal blood pressure, the incidence rate of their children is only 3%. Animal experimental studies have successfully established a genetic hypertension rat model, and after several generations of breeding, almost 100% of them develop hypertension. With the completion of the human genome project, the study of genetic genes has entered the post-genomic era. A hypertension gene study focusing on the location, identification and cloning of susceptibility genes for primary hypertension is developing rapidly. This study aims to fundamentally elucidate the genetic nature of primary hypertension. If successful, it will have a revolutionary impact on the clinical classification, prognosis, individualized treatment, and early detection and prevention of susceptible patients of primary hypertension.

At present, more than ten pathogenic genes of monogenic secondary hypertension have been successfully cloned or located. Diseases in which pathogenic gene mutations have been detected include Liddle syndrome and Gordon syndrome. The pathogenic genes of these diseases mainly involve genes related to adrenal cortex hormone metabolism, ion transport, catecholamine metabolism, etc. The study of monogenic secondary hypertension pathogenic genes has promoted the functional study of the relationship between pathogenic gene mutations and the mechanism of hypertension, and provided important clues and a good start for the study of genes related to primary hypertension. In terms of primary hypertension susceptibility genes, the number of hypertension susceptibility genes has increased to dozens. Based on the existing physiological and pathophysiological knowledge, the susceptibility genes involved in the blood pressure regulation mechanism involve: renin-angiotensin-aldosterone system, sympathetic nervous system, endothelin, sodium-receptor peptide, as well as lipid metabolism, apolipoproteins, ion channels or transporters, such as angiotensin (AGT) gene, angiotensin converting enzyme (ACE) gene, angiotensin II-I receptor (AT Ⅰ) gene, endothelin 2 (ET-2) gene, endothelial nitric oxide synthase (eNOS) gene, atrial fibrin family genes (ANP and NPRC), etc.