What are the dangers of anti-sperm antibodies greater than 250?

We know that a healthy baby is not only the future of the country, but also a happy thing for a family. But once infertility occurs, it is often a very painful and painful thing. In infertility, both men and women may have anti-sperm antibodies. What are the dangers of anti-sperm antibodies greater than 250?

In men, the main symptoms are decreased sperm quality, decreased motility, substandard motility, and even the appearance of a large number of deformed sperm, causing some seemingly healthy men to lose their normal reproductive ability without realizing it, although they feel very surprised and helpless.

In women, AsAb can kill, phagocytose, agglutinate and inhibit sperm, which often causes fatal "frustration" in the combination of sperm and egg. It can be said that "one yang" is blocking all sperms, and sperms are reluctant to enter the female reproductive tract. Normal fertilization cannot occur and sperm rejection occurs. Even if pregnancy occurs, it often leads to miscarriage and premature birth, which seriously interferes with fertility. The harm of antisperm antibodies is that they damage sperm (1) Antisperm antibodies bind to cervical mucus proteins and prevent sperm from passing through cervical mucus.

(2) Antisperm antibodies can interfere with the ability of sperm to react with the acrosome, affecting sperm motility. (3) Cytotoxicity, through complement-mediated phagocytosis of sperm.

(4) Antisperm antibodies can prevent sperm and egg from combining, causing complement-mediated lysis of the fertilized egg, damaging embryo implantation and early embryo development, and leading to early miscarriage. Folding causes miscarriage because there are also sperm antigens on the early embryo, and antisperm antibodies react with them and mediate complements, macrophages and killer cells to kill the fertilized egg and early embryo, thus leading to miscarriage.

Warm reminder: In this case, further active treatment is generally needed. However, for the sake of health, drug treatment is not recommended for anti-sperm antibodies greater than 250. Patients with anti-sperm antibodies greater than 250 can actually insist on using condoms for 3-6 months. And it is easier to conceive when the titer of anti-sperm antibodies in the body decreases.