Sperm hypospermia test

The sperm hypospermia test is a way to test the quality of male sperm. Through this test, the survival rate of male sperm can be well judged, and it can also help infertile patients find out the cause of infertility. Therefore, the application of sperm hypospermia test in clinical medicine is still relatively extensive. Below, we will introduce the relevant knowledge of sperm hypospermia test in detail!

1. Introduction to the Sperm Hypoosmotic Swelling Test

The sperm hypoosmotic swelling test, also known as the sperm tail hypoosmotic swelling test (HOST), was created by Jeyendran in 1984 after he found that the tail of human sperm exhibited different types of swelling in a hypoosmotic solution. This phenomenon reflects the physiological function of the sperm membrane and is related to sperm energy metabolism, fertilization, capacitation, apicosome reaction, and the fusion of sperm and egg membranes. The sperm tail is the sperm's movement organ. After the sperm is ejaculated into the vagina, it ascends through the cervix and uterine body, and finally reaches the fallopian tube and combines with the egg cell. To complete the above movement, a well-functioning sperm tail is required. Clinically, the survival rate of sperm can be evaluated by testing the integrity of the sperm membrane. When sperm is in a hypotonic solution, water molecules can enter the sperm through the sperm membrane, causing the sperm to increase in size and swell, especially the tail of normal sperm. Sperm with incomplete membranes or dead sperm generally do not swell.

2. Clinical significance of sperm hypoosmotic swelling experiment

The morphological integrity and functional activity of sperm membrane are important factors in the fertilization process. The sperm hypoosmotic swelling test is an in vitro test method that can evaluate the functional integrity of sperm membrane and is an effective method to evaluate sperm fertility.

Routine semen analysis, such as sperm density, motility and morphological examination indicators, is sometimes not enough to fully identify the cause of infertility. Therefore, clinical research on sperm function, such as sperm membrane function, has become increasingly important. Sperm membrane function is closely related to sperm metabolism, acrosome reaction, sperm capacitation and sperm-egg fusion, and has important guiding significance for the diagnosis and treatment of clinical male infertility.

3. What is the cause of low sperm osmosis and swelling?

The hypoosmotic swelling test, also known as the hypoosmotic swelling test (HOST), was created by Jeyendran in 1984 after he discovered that the tail of human sperm exhibited different types of swelling in a hypoosmotic solution. This phenomenon reflects the physiological function of the sperm membrane and is related to sperm energy metabolism, fertilization, capacitation, acrosome reaction, and the fusion of sperm and egg membranes.