Causes of hyperthyroidism exophthalmos: these three points are worth paying attention to

Hyperthyroidism exophthalmos is a common disease in life. After discovering that you have hyperthyroidism exophthalmos, you need to know more about the cause of your disease. So, what are the causes of hyperthyroidism exophthalmos?

1. Genetic factors:

Human cell compatibility antigen is closely related to exophthalmos. The positive HLABgDR3 locus in hyperthyroidism patients with exophthalmos is significantly higher than that in hyperthyroidism patients without exophthalmos.

2. Environmental factors:

After observing patients with hyperthyroidism, it was found that 83% of those with exophthalmos smoked, while only 40% of those without exophthalmos smoked, suggesting that smoking may be involved in the occurrence of exophthalmos. This is one of the causes of exophthalmos in hyperthyroidism.

3. The role of post-ocular fibroblasts:

Immunohistochemical staining shows that IGF-I exists in extraocular muscles, fat cells, and inflammatory infiltrating cells. IGF-I and fibroblast growth factor have the effect of stimulating fibroblasts. Therefore, the cause of hyperthyroidism exophthalmos is related to this.