Chronic renal insufficiency, four different medical stages

In daily life, if a man has progressive kidney disease and does not receive timely treatment, he may eventually develop chronic renal failure. There are many causes of this disease, such as chronic glomerulonephritis, kidney damage caused by metabolic abnormalities, etc. In medicine, chronic renal failure is divided into 4 different stages.

1. Kidney function compensation period

Main manifestations: When the glomerular filtration rate is ≥ 1/2 of the normal value, blood urea nitrogen and creatinine do not increase, the body's metabolism is balanced, and no obvious symptoms appear.

2. Renal insufficiency

Main manifestations: glomerular filtration rate <50% of normal value, blood creatinine level rises to above 177μmol/L (2mg/dl), blood urea nitrogen level rises to >7.0mmol/L (20mg/dl), patients have symptoms such as fatigue, loss of appetite, frequent urination at night, mild anemia, etc.

3. Renal failure stage

Main manifestations: When the endogenous creatinine clearance rate drops below 20 ml/min, the BUN level is higher than 17.9-21.4 mmol/L (50-60 mg/dl), and the blood creatinine rises to above 442 μmol/L (5 mg/dl), the patient will experience anemia, increased blood phosphorus level, decreased blood calcium, metabolic acidosis, water and electrolyte disorders, etc.

4. End-stage uremia

Main manifestations: Endogenous creatinine clearance is below 10ml/min, blood creatinine rises to above 707μmol/L, acidosis is obvious, symptoms of various systems appear, and even coma occurs.